In what part of the body do cancerous cells primarily take over in Acute Myeloid Leukaemia?

In Acute Myeloid Leukaemia (AML), cancerous cells primarily take over in the bone marrow. The bone marrow is responsible for producing blood cells, including red blood cells, white blood cells, and platelets. In AML, the normal process of blood cell production is disrupted by the uncontrolled proliferation of myeloid cells, leading to an accumulation of abnormal white blood cells.

These cancerous cells replace the healthy cells in the bone marrow, resulting in a diminished production of normal blood cells. This can lead to a variety of complications, such as anemia, increased risk of infection, and issues with clotting. Thus, the correct answer is that the bone marrow is the key site for the development and progression of AML.