How is Non-Hodgkin lymphoma typically diagnosed?

Non-Hodgkin lymphoma is typically diagnosed through a biopsy of lymphatic tissue, which is the most definitive method. A biopsy involves taking a sample of tissue from an affected lymph node or other relevant area. This tissue is then examined microscopically to identify the presence of cancerous cells, which is crucial for determining the specific type of lymphoma.

The importance of this method lies in its ability to provide direct evidence of the disease, allowing for more accurate diagnosis and staging. While blood tests, imaging studies, and physical examinations can provide initial information and indicate the possibility of lymphoma, they do not offer the conclusive diagnostic evidence that a biopsy does. Therefore, obtaining a tissue sample is vital for confirming the diagnosis and guiding treatment options effectively.